BrainPill claims to be the best nootropic supplement you can find today. It is true that it includes some impressive ingredients, but unfortunately, the formula does not seem to work as effectively as you might want. It may be because some of its ingredients are under-dosed and others do not have any scientific evidence to support their claims. Here is more about why we think you will be better off trying other supplements to boost memory and brain function.
The official site states:
Your brainpower peaks around age 30. After, your brain begins to shrink and slow down, effects that catch up with you in your 40s and 50s.
However, there is not enough evidence to support this statement. Some scientists consider it true, but others do not. A study has actually found that your brain will not deteriorate much in terms of size if your brain is otherwise healthy and you do not have a brain disorder or disease like, dementia or Alzheimer’s disease. It means that you do not need BrainPill just because they say that your brain will shrink with age.
Even if you have a look at the ingredient profile of BrainPill, you will not find much evidence to support those claims made by the manufacturer. One of its active ingredients is Cognizin, which is a proprietary blend and is supposed improve your focus. In reality, Cognizin only provides you with a patented form of citicoline, which is supposed to help supply your brain with enough energy to stay sharp. There is some evidence that supplementing with citicoline may help improve memory and overall brain health, but that only happens when you take enough of it.
One 2012 research study from Food and Nutrition Sciences, working with healthy adult women aged 40–60 showed that after 28 days of citicoline supplementation the women had 600% fewer mistakes than the placebo group!
Studies show that you need to take more than 1000 mg of citicoline to improve thinking skills, whereas you should at least be getting 600 mg/day to treat brain disease. You get 500 mg of citicoline from BrainPill, which is certainly not going to make a huge difference to your brainpower.
BrainPill also includes 320 mg of Synapsa, which is supposed to improve your cognitive performance. The company says that Synapsa helps make it easier to recall information, but not enough scientific evidence is there to support this claim. It is worth mentioning that Synapsa is basically a patented form of Bacopa Monnieri or Brahmi, which contains bacosides or Bacopin that are supposed to affect neurotransmitters in the brain.
You cannot find enough scientific evidence to confirm that bacopa monnieri can help enhance memory. In fact, studies have offered mixed results.
Two double-blind clinical trials found some memory-enhancing and mental-function benefits, according to reports in psychopharmacology in 2001 and neuropsychopharmacology in 2002.
However, that does not mean you can take bacopa monnieri and hope to improve brain function because other studies do not confirm its benefit.
A double-blind trial published in Human Psychopharmacology in 2001 found no benefits in memory or mental function, notes the University of Pittsburgh Medical Centre.
Moreover, some studies have found that whatever little effect bacopa monnieri offers is because of the fact that it helps lower anxiety. It may not work for you if you are not looking for a way to reduce anxiety. It is also fat soluble, which means you need to take it with a lipid source or you are not going to get good results. Another issue is that even if you think that bacopa monnieri actually offers any memory-boosting benefits, you are less likely to get it from BrainPill. The reason is that you should be taking at least 450 mg a day but you do not get more than 300 mg from BrainPill.
How to Take BrainPill
There are 60 capsules in each bottle and you have to take two capsules once a day.
BrainPill also contains Huperzia Serrata or Huperzine A to help improve alertness. The neurotransmitter acetylcholine is responsible for keeping you focused and alert, and Huperzine-A is supposed to help prevent the breakdown of this neurotransmitter in your brain. While there are some studies showing that Huperzine-A may help people with Alzheimer’s disease, most of these studies are limited by weak study design.
In a study involving a total of AD 454 patients, it was found that HupA might have some beneficial effects on improvement cognitive function, global clinical status, and functional performance.
However, it was rejected by a Cochrane Review in 2008 because of the following:
The methodological quality of most included trials was not high and that only one study was of adequate quality and size. The authors conclude that further large randomised multi-centre trials are warranted.
Here, it is important to mention that some experts believe that you should actually avoid using Huperzine-A in certain cases for the treatment of Alzheimer’s disease. For instance:
The Mayo Clinic states:
The Alzheimer’s Association recommends that you not take huperzine A if you’re already taking a prescribed cholinesterase inhibitor, such as donepezil (Aricept), rivastigmine (Exelon) or galantamine (Razadyne). Taking both could increase your risk of serious side effects.
So, there are contradictory results regarding the efficacy of Huperzine-A for the treatment of AD, and there is nothing much that it is going to help otherwise healthy individuals prevent brain deterioration. The same holds true for Vinpocetine, which is another ineffective ingredient to boost memory.
BrainPill includes Vinpocetine to help improve blood flow to your brain. While it is good to have more blood directed towards your brain, this is not always going to help boost memory in a short time. The claim that Vinpocetine increases memory has not been investigated scientifically. Even if it offers some benefits, that happens only when you take up to 30 mg/day, but you do not get more than 5 mg of Vinpocetine from BrainPill, which is never going to make any difference to your memory or cognitive function.
- Under-dosed, ineffective ingredients
- Few positive reviews
- Very expensive
BrainPill also has Phosphatidylserine, a type of fat found in brain cells. There is some evidence that supplementing with it may improve memory in people suffering from dementia. However, that study used Phosphatidylserine (PS) obtained from cow brain, which is no longer possible after the advent of mad cow disease. Moreover, there is no clinical data to confirm that PS can help prevent dementia in healthy people. Another issue is that studies showing benefits of Phosphatidylserine have used up to 300 mg of PS per day divided into three doses. You only get 5 mg of PS from BrainPill, which makes it quite ineffective.
Another ingredient found in BrainPill is Ginkgo Biloba, which is supposed to improve memory but fails to deliver in the real world. It has been studies extensively for its brain-boosting properties, but the evidence is still inconsistent.
A small Italian study in 2006 found ginkgo as effective as donepezil (Aricept) in improving memory and attention in people with mild to moderate Alzheimer’s. However, a review of 35 studies by the Cochrane Collaboration in 2007 concluded that the overall evidence for ginkgo as a treatment for dementia or cognitive impairment is “inconsistent and unconvincing.
There are some other ingredients too but they are also ineffective or under-dosed. L-tyrosine, for instance, is supposed to relieve stress by producing noradrenaline and dopamine, but that is only when you take more than 500 mg an hour before exercise. Moreover, BrainPill includes B-vitamins but there is no good evidence that supplementing with vitamins can prevent or delay mental decline.
Overall, BrainPill does not have what it takes to boost your memory and cognitive function, and it certainly is not a great choice considering how expensive it is. You can easily get another high quality nootropic supplement with scientifically proven ingredients at a much lower price. So, avoid it and try something else!
What Does BrainPill Claim To Do?
BrainPill promises so many benefits and helps improve all parts of your brain. Through regular use, you will be able to have a better working memory. Here are some of its claimed benefits:
- It helps boost your memory.
- It makes it easier for you to process memory.
- It helps you work without having to deal with distractions.
- It helps make effective decisions with fewer chances of errors.
Does BrainPill Work?
The ingredient profile of BrainPill may look impressive, but the truth is it is not going to result in any significant improvement in your memory. Some of its ingredients do not have any scientific backing, such as Huperzine-A, ginkgo biloba, and B-vitamins. Other ingredients are under-dosed, such as Vinpocetine, L-tyrosine, and even Cognizin. You may notice some results in the beginning, but it is certainly not something that will help you on a long-term basis. It is certainly not effective in preventing brain deterioration, so you should look for something else to help boost your brainpower and cognitive skills.
Does BrainPill Have Any Side Effects?
BrainPill is considered safe because it includes natural ingredients, but the addition of certain herbs and proprietary blends makes it less suitable for many. You should avoid it when you are pregnant or breastfeeding. You may want to avoid it when you already have an existing medical condition.
BrainPill contains citicoline that may cause certain side effects, such as blurred vision, chest pains, headaches, insomnia, and low blood pressure. You may also experience gastrointestinal discomfort after using BrainPill, and that is mainly because of B-vitamins, bacopa monnieri, and ginkgo biloba.
Ginkgo is also associated with several other issues, such as bleeding of the eyes, blurred vision, constipation, distortion of taste, oedema, dry mouth, dizziness, and bruising. Similarly, bacopa monnieri may lead to increased thirst, stomach cramping, dry mouth, nausea, palpitations, and increased bowel movements.
Avoid if you are pregnant, breast-feeding or suffer from any medical conditions.
Are There Any Customer Reviews For BrainPill?
BrainPill does not have many positive reviews, which is always a cause for concern. Here are some examples of issues experienced by customers:
I am taking BrainPill for the last three weeks now and I have not noticed any significant change in my memory.
It is very expensive and I just cannot keep buying more to get positive results. Will look for other supplements.