New supplements are being developed and introduced constantly into an increasingly crowded market, but obviously not every company and supplement are going to be successful. Some products are taken off the shelves and some companies close down, often with little or no notice, leaving customers disappointed when they try to reorder supplements.

Cognitine, formerly known as Cognizine, is a nootropic supplement that was claimed to ‘help learning, memory, focus, and concentration’, but is no longer available, due to its manufacturing company shutting down in 2016.

Cognitine Pros

  • Uses common ingredients

Cognitine Cons

  • Company accused of making false claims
  • No longer available
  • Company closed overnight leaving customers with unfulfilled orders
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What You Need To Know About Cognitine

Cognitine, formerly known as Cognizine, is one of the products once manufactured by Legacy Labs, a supplement manufacturer who closed in early 2016. Cognitine was designed to act as a nootropic supplement, focusing particularly upon improving memory. The company seemingly targeted their advertising towards the elderly, and they attracted attention from advertising bodies for overstating the benefits of their supplements.

What Are The Side Effects Of Cognitine?

There is a relatively long list of ingredients found in Cognitine, and they can cause a range of side effects. The most common side effects appear to be stomach pain, nausea, sleep disturbances, headache, dizziness, and digestive issues such as constipation and diarrhoea.

For a full list of the side effects that could be caused by Cognitine, click on the Side Effects tab below.

How Much Does Cognitine Cost?

Legacy Labs appear to have closed permanently, and have taken down their official website. As the Legacy Labs website was the only remaining place to purchase their supplements from, Cognitine is not available to purchase at all anymore.

Even when Cognitine was available to purchase, it was incredibly expensive. A single bottle cost $67, two bottles cost $119.90, and an order of four bottles cost $199.80. Finally, a bulk purchase of ten bottles would have cost $379.50. We have seen numerous other nootropic supplements with similar ingredients lists (sometimes even featuring more ingredients as well) that cost far less than Cognitine.

Our Verdict On Cognitine

Obviously Cognitine being unavailable and the manufacturing company being out of business are both huge issues that mean that we cannot recommend this product to our readers. However, even if Cognitine was still available, we would still not recommend the nootropic.

Legacy Labs, the manufacturers of the supplement, were accused numerous times of overstating the benefits of Cognitine, leading to one advertising regulations body investigating the company and advising them to change their descriptions of the benefits of the supplement.

Although the company did offer a money back guarantee whilst they were still in business, when they closed down, there were some customers who never received their orders, and who were unable to contact the company to obtain a refund. The company also has a D+ rating on the Better Business Bureau website, along with numerous complaints about them. Older third party reviews indicate that Legacy Labs used to have an F rating with the BBB; and there are many customer reviews online showing how poor their reputation was for customer service.

Cognitine’s ingredients list features a lot of popular nootropic ingredients, including Bacopa Monnieri, Vinpocetine and Phosphatidylserine, which are all available in many other nootropic supplements, typically at a much lower cost than Cognitine was being sold for. They may be somewhat effective at boosting various aspects of cognitive function, but the amount of available clinical support varies hugely between ingredients. Remember that nootropics are a relatively new type of supplement, and the industry takes a lot of information from studies on Alzheimer’s patients and patients with life-altering brain injuries, in the hopes that the ingredients will also offer cognitive benefits to the wider population.

Overall, we do not recommend Cognitine to our readers.

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Cognitine Review

Cognitine is a nootropic supplement that, according to the manufacturers, would ‘help learning, memory, focus, and concentration’. The supplement is no longer available, as the manufacturers are no longer in business as of March 2016.

Cognitine Facts

  • Manufactured by Legacy Labs LLC
  • 60 capsules per bottle
  • Company no longer in operation

Cognitine was manufactured by Legacy Labs, who were based in Nevada. The company appear to be uncontactable, as they took down their official website and disconnected their phone number when the business closed. The company had a Better Business Bureau rating of D+, and numerous complaints against the company, including their billing practices and customer service.

How to Take Cognitine

As a dietary supplement, take one tablet twice per day between meals, no later than 4 pm. If recommended by a nutritionally informed physician, four tablets per day may be beneficial.

Cognitine was previously known as Cognizine; the name change came after a Canadian pharmaceutical company launched a lawsuit against Legacy Labs, as the word Cognizine infringed on their pre-existing and copyrighted product, COGNIZIN. The manufacturers have also been investigated by an Advertising Standards Body, after they received complaints that the advertising for Cognitine contained unsubstantiated claims that were unproven and exaggerated.

Cognitine Concerns:

  • No longer available
  • Manufacturers had an incredibly poor reputation
  • Company accused of overstating benefits of supplement

What Does Cognitine Claim To Do?

Legacy Labs, the manufacturers of Cognitine, made the following claims about the benefits of the supplement:

‘Cognitine is a complete brain support formula designed to support cognition through every stage of life. Cognitine provides essential daily neurotransmitter support and additional nutraceuticals that help learning, memory, focus, and concentration.’

[The misspelling of ‘nerotransmitter’ is that of Legacy Labs, not ours.]

A promotional video presentation (that is no longer available) also reportedly made the following claims and statements about Cognitine:

  • Eliminate Senior Moments
  • Feel Focused, calm and clear, every day, all day long
  • Improve your mood and productivity
  • Think faster, effortlessly express yourself better
  • Bring Fresh Blood Flow to your Oxygen Starved brain
  • Dust off your neurotransmitters and experience a surge in memory and concentration
  • Make your most important organ a FULL 12 Years younger (can you really afford not to?)

Does Cognitine Work?

Bacopa Monnieri needs to be taken daily for an effect to build up over time, but some of the other ingredients could cause a general improvement in energy levels and mental clarity shortly after taking the supplement.

Bacopa Monnieri reduces anxiety and improves memory. Vinpocetine could both help to improve mental energy and memory, but the clinical evidence is generally inadequate, as the trials that have been conducted are extremely limited, biased and outdated.

Huperzine A could help to boost cognitive function.

Phosphatidylserine has clinical support linking it with the treatment of cognitive decline, but there is no strong evidence linking it with improved cognitive function in those who are not cognitively impaired (such as those suffering from Alzheimer’s).

DHA may also increase blood flow to the brain, which could potentially aid mental focus and clarity. However, the clinical evidence for this is based upon only one study, and the doses used were unstated.

Overall, there is some clinical support for the ingredients in Cognitine aiding with some aspects of cognitive function, including memory and mental energy. However, we have seen other nootropic supplements that contain all of the ingredients found in Cognitine, as well as containing other, more potent nootropic ingredients (that also have much more clinical support behind them).

What Are The Ingredients of Cognitine?

The ingredients used in Cognitine are detailed below. The ingredient quantities listed are per serving of two tablets.

  • Bacopa Powder: Used to reduce anxiety, improve memory, and seems to have a minor ability to treat depression, making it a general mild mood booster. The effects can take time to achieve a noticeable level, as the effects appear to accumulate with repeated use.
  • DHA Concentrate: Short for docosahexaenoic acid. Fish oil rich in DHA may improve blood flow to the brain, and could benefit ‘certain aspects of mental performance in young adults’.
  • DMAE: This ingredient is marketed as a memory and mood enhancer. There is currently little clinical evidence to support this.
  • Korean Ginseng Root Powder: More commonly known as Panax Ginseng. Panax Ginseng is associated with improved cognition in fatigued subjects and slight decreases in muscle damage after exercise. It also appears to reduce fatigue, and consumers report feeling calmer after consumption.
  • L-Glutamine: An essential amino acid, which is a building block of protein (muscle).
  • Ginkgo Biloba Leaf Extract: Appears to improve circulation, and may help to kill bacteria in the body that could cause infections, although it is used as an herbal remedy to treat a range of ailments.
  • Phosphatidylserine: Several studies with phosphatidylserine indicate improved cognitive abilities and behaviours, but the studies focused on Alzheimer’s patients; it is possible that these effects could also benefit consumers in general, but there is no real clinical support to support this. The FDA has stated that Phosphatidylserine may reduce the risk of cognitive dysfunction and dementia in the elderly.
  • Vinpocetine: Because it is an entirely synthetic chemical that requires significant lab work to produce, there is some debate as to whether this ingredient actually qualifies as a supplement under US and FDA guidelines. Vinpocetine may increase blood flow to the brain, and so may help to treat fatigue and improve memory; despite claims about research being extensive, most research is outdated and uses biased research methods.
  • Huperzine: Huperzine-A is thought to be a cognitive enhancer. Because of the relatively long half-life of this compound, its use should be cycled, with breaks in usage every few weeks.

Does Cognitine Have Any Side Effects?

Many of the ingredients found in Cognitine could potentially cause some side effects in some people.

Studies have shown that Bacopa leaf causes upset stomachs in participants much more than placebos. This has led to the recommendation that this ingredient be taken with a meal, rather than on an empty stomach, as this will minimise the chances of getting an upset stomach. It may also cause nausea, cramping, bloating, and diarrhoea.

Side effects of Phosphatidylserine can include insomnia and stomach upset, particularly at doses over 300 mg. It can be made from either plant or animal sources, and so may not be suitable for vegetarians.

Vinpocetine can cause some side effects including stomach pain, nausea, sleep disturbances, headache, dizziness, nervousness, and flushing of the face.
Huperzine A can cause some side effects such as nausea, diarrhoea, vomiting, sweating, blurred vision, slurred speech, restlessness, loss of appetite, contraction and twitching of muscle fibres, cramping, increased saliva and urine, inability to control urination, high blood pressure, and slowed heart rate.

DMAE can cause constipation, itching, headaches, drowsiness, insomnia, excitation, vivid dreams, confusion, depression, increased blood pressure, an increase in schizophrenia symptoms, and unwanted movements of the face and mouth.

Do not use this product if you are pregnant, nursing, or under the age of 18. It is strongly recommended that you consult your physician if you are taking medication or have a medical condition, as taking this product may be a concern for some people. Do not exceed recommended intake. If you experience any adverse reaction to this product immediately discontinue use and contact your physician. Do not use if you are using a MAOI, prescription drug, or over-the-counter drug. If you are a competitive athlete and/or subject to drug testing, consult with your sanctioning body prior to use to ensure compliance. Use cautiously in patients with history of seizures, based on reports of seizures due to Ginkgo seed ingestion.

Are There Any Customer Reviews For Cognitine?

We found numerous customer reviews for Cognitine online, with some people loving the supplement and others finding that it offered no perceivable benefits at all. We also found some complaints from customers who ordered their products shortly before the company went out of business, but never received the products, and were unable to contact the company to get a refund.

Taken it for two months … totally waste of money.

I purchased their Cognitine a year ago and found it to be extremely effective, though expensive. Since then I have found nothing that was anywhere as good, but when I tried to locate a way to get more of the product, I am having a difficult time. Their customer service number is out of service and I can find no way to contact them either in Vegas or anywhere else. I would like the product again as it really did work very well.

I received several bottles and gave a bottle to a friend. My friend told me it had no effect. For me my blood pressure went sky high and so I stopped taking it. This is a fraud. I would not recommend it to a friend.

I have used this product for several months. I found that if I missed two or three days, there was a definite effect on my memory. It took longer to remember the word I was looking to say, and little thing slipped my mind unless I was reminded by someone else. I can’t speak for anyone else so I don’t guarantee it works for everyone, but it sure works for me and I don’t want to be without it. I am 78 years old and whatever I can do to keep my mind sharp I will do.

I started taking Bacopa and it helped quite a bit. When I found Cognitine, I saw it had Bacopa and a bunch of other good supplements all in one, so I ordered it. It was a little pricey for me, but I figured you probably can’t buy all these things separately and pay a lot less. Works even better than just Bacopa. Mental fog is pretty much gone.

Does Cognitine Offer a Money-Back Guarantee?

The manufacturers of Cognitine, Legacy Labs, did offer a money back guarantee whilst they were in business. However, the company appears to have closed permanently in March 2016 with no notice, leaving some customers without their ordered products, and unable to get a refund.

Where Can I Buy Cognitine?

Legacy Labs appear to have closed permanently, and have taken down their official website. As the Legacy Labs website was the only remaining place to purchase their supplements from, Cognitine is not available to purchase at all anymore.

Even when Cognitine was available to purchase, it was incredibly expensive. A single bottle cost $67, two bottles cost $119.90, and an order of four bottles cost $199.80. Finally, a bulk purchase of ten bottles would have cost $379.50.

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1.5 out of 5
Editor's Rating
  • Effectiveness
  • Safety
  • Price / Guarantee
The most popular consumer choice in 2021 is OmniMind

Containing ingredients that have been clinically tested and boasting a 30-day money-back guarantee, OmniMind is quickly rising to the top of the nootropic world.

Find out why people are choosing OmniMind to achieve advanced brain performance, and why it's our editor's top pick.

Read the Nootropic Watchdog OmniMind review here.

Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.

Have Your Say

1 comment on 'Cognitine'

  1. I tried Cognitine and was very impressed. The results were immediate and noticeably effective. I had delays in remembering words, items, names of things that should be very familiar, and after the first dose of Cognitine, the words popped into my mind instantly. I was every disappointed when I was no longer able to get the product. Have not found anything that works as fast or effectively since, although I have been trying different products that promise the same results.

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