DEPLIN

Rating
DEPLIN is a dietary supplement that targets users with shifting amounts of despondency. The main component of this supplement is L-methylfolate, and it is for enhancing the effects of other medications meant for tackling with depression and related symptoms. Typically, DEPLIN works by dealing with monoamines, which are connected with one’s disposition. L-methylfolate works as the dynamic and readily usable folate that our body metabolizes from folic corrosive.

Manufactured by Pamlab, this supplement is a remedy vitamin that is utilized to expand the capability of both antipsychotics and upper meds. DEPLIN is used for incrementing the folate levels in people suffering from depression and despondency. This supplement also diminishes homocysteine levels in the users with schizophrenia.

DEPLIN Pros

  • This supplement contains activated folate
  • Supports antidepressant therapy to treat depression

DEPLIN Cons

  • Cost of this supplement is comparatively high
  • A prescription is required to purchase this supplement
  • The manufacturer doesn’t offer any money back guarantee
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What You Need To Know About DEPLIN

DEPLIN is a prescribed supplement containing L-methylfolate, which is the active dietary form of folate or vitamin B9 commonly used by the brain. Folate is mostly found in legumes, green leafy vegetables, some types of fruits, nuts and orange juices. The human body needs to digest and process the synthetic B9 before this gets converted to the active form L-methylfolate. As DEPLIN is the active type of folate, it is readily usable by the body. It helps create all the chemicals required for dealing with depression.

What Are The Side Effects Of DEPLIN?

Some of the serious side effects of this supplement are swelling/itching, mainly in the areas like face, throat and tongue, rash, trouble breathing, and dizziness.

How Much Does DEPLIN Cost?

Deplin is expensive and it can only be purchased via prescription. One month supply of this supplement can cost around $98 depending on your location. Though there are no online retailers selling this product, there are some websites that offer discounts and coupons for the buyers.

Our Verdict On DEPLIN

As mentioned by the manufacturer, DEPLIN mainly works by addressing all the imbalances in the key neurotransmitters in the brain. It uses folic acid to combat depression, except in this case it offers so in the activated folate form. This makes it readily available for the body to benefit from.

However, this supplement has received mixed reviews on the web. A number of users found the results satisfactory while some have reported poor or no results after usage. Some have also reported side effects. Add to this the lack of money-back guarantee and the expense of the product, we do not recommend DEPLIN.

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DEPLIN Review

DEPLIN is basically the brand name of a supplement that includes l-methylfolate and B vitamin as its active ingredients. This medical food is a product approved by Food and Drug Administration (FDA) and is used to combat depression along with other various health issues caused by different nutritional deficiencies. The formulation of this supplement is capable of penetrating the blood brain barrier, this means that it has the power to affect altering mood. To get the maximum benefits, users need to consume this supplement on a daily basis.

DEPLIN Facts

  • DEPLIN can be used in people suffering from major depressive disorder or who are suffering from folate deficiency
  • People with schizophrenia can use this supplement, who have hyperhomocysteinemia regarding folate deficiency
  • It has been approved by the FDA

As a source of the single bio-available form of Folate that can cross the blood brain barrier (BBB), DEPLIN is for not just depression but for other nervous system related conditions as well. Classified as a medical food instead of a drug, this supplement allows the folate to get converted to L-methylfolate easily. This therefore creates norepinephrine, serotonin and dopamine in the brain. Numerous studies over the years have proven that these are responsible for combating depression, for balancing mood and calming the mind leading to positive actions.

How to Take DEPLIN

This supplement can be consumed orally with or without food as directed by the physician. Generally, it is advised to consume this supplement once a day. To get the maximum benefits, users need to consume this supplement on a daily basis. But the dosage entirely depends on the medical condition of the users as well as on their response to treatment. So, consult with your doctor before starting this supplement and don’t increase the dosage level without information or take this product more often than what is directed. But in case you are purchasing this supplement as an over-the-counter product, then follow all the instructions mentioned on the package.

Being known as the derivative of folate or B9, DEPLIN works as a strong tool for treating chronic despondency. This supplement is often prescribed to treat people suffering from various types of depression. Since it takes the path of dietary management of depression it therefore regulates all the monoamine neurotransmitters connected to mood. By increasing the folate presence it affects the brain positively, and stems the wave of depression that can overwhelm one and affect the quality of their lives.

DEPLIN Concerns:

  • Cost of this supplement is comparatively high
  • A prescription is required to purchase this supplement
  • The manufacturer doesn’t offer any money back guarantee

Often this supplement is used along with some other anti-depressant medications in people who have low folate levels or major depressive disorders. According to the manufacturer Pamlab, this supplement can also be used to treat other health conditions connected to low folate levels, pregnancy, gastrointestinal problems, liver disease and alcoholism.

What Does DEPLIN Claim To Do?

DEPLIN is developed and manufactured by Pamlab, a company that specializes in offering “prescribed medical foods”. According to the manufacturer, this product addresses the nutritional imbalances successfully that are caused by depression. Specifically, this supplement offers the users with increased amounts of active folate. This works along with the antidepressant therapy to treat depression as well as to prevent it from recurring. The manufacturer claims that this supplement can also be used to treat other health conditions connected to low folate levels pregnancy, gastrointestinal problems, liver disease and alcoholism.

Does DEPLIN Work?

Going by the various reviews, it seems that the supplement can work. It works by boosting the body’s ability to boost the neurotransmitters. Extra neurotransmitters like norepinephrine, serotonin and dopamine empower the upper and make it more viable. DEPLIN mainly holds 7.5 mg of L-methylfolate, which is the main dynamic kind of folate that can actually cross the blood barrier. While studies have proven the efficacy of the ingredients, some user reviews have not claimed to have seen the results they expected.

What Are The Ingredients of DEPLIN?

DEPLIN 15mg is the combination of active ingredients like Silicified Microcrystalline Cellulose 90, Dibasic Calcium Phosphate Dihydrate, Opadry II Orange 85F43102, PEG 3350, (Polyvinyl Alcohol, Titanium Dioxide [color], FD&C Yellow #6[color], Talc, FD&C Yellow #5[color], FD&C Blue #2[color]), FD&CRed #40[color], magnesium stearate (vegetable source), carnauba wax and L-methylfolate Calcium.

Together they offer activated folate that is readily usable by the body and helps it to boost the neurotransmitter levels.

Does DEPLIN Have Any Side Effects?

Since this supplement has not gone through any clinical testing, the exact side effects are still unknown.

Some common side effects that one can experience after using these pills are:

  • Loss of appetite
  • Nausea
  • Gas
  • Bloating
  • Bitter taste in the mouth

Apart from that, there can be some serious signs of allergic reactions like difficulty in breathing, hives, swelling of the lips, face, throat or tongue.

If anyone does face these symptoms then he or she should contact a healthcare practitioner immediately.

Caution:
Warning:
DEPLIN can have severe negative effects for certain health conditions. Users must inform their pharmacist or doctor in case they are going through any medical issues. Here are the details:
In case you are allergic to any foods, medicines or other substances then this supplement is not for you.
In case you have low level of vitamin B12 in the blood or have anemia, then you must consult with your physician before consuming it.
In case you are planning to have a baby, are pregnant or are nursing, then you will have different dosage for this supplement. Therefore, it is better to communicate to the health practitioner to learn about the correct dosage.
If you are consuming any other prescribed or non-prescribed medicines, dietary supplements or herbal preparations, there might be interactions so caution is advised.

Are There Any Customer Reviews For DEPLIN?

There are numerous user reviews for DEPLIN on the web. These are available across retail sites, review sites as well the official website.

Does DEPLIN Offer a Money-Back Guarantee?

Nothing is mentioned in the manufacturer’s site about a money back guarantee.

Where Can I Buy DEPLIN?

The official DEPLIN website provides detail information for purchase.

DEPLIN is not readily available on any other retail outlets. But this can be purchased from Brand Direct Health Pharmacy, which is the mail order partner of this manufacturer.

DEPLIN

2 out of 5
Editor's Rating
  • Effectiveness
  • Safety
  • Price / Guarantee
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The most popular consumer choice in 2019 is OmniMind

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Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.

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1 comment on 'DEPLIN'

  1. The point of L-methylfolate is that it’s the metabolically active form and able to cross the blood-brain barrier. It’s absolutely irrelevant and a waste of money for most people- (you know, like a gluten free diet for people who believe it’s somehow healthier to avoid gluten even though they have no reason they should- go ahead and edit that out if you want to) because they can metabolise enough of the racemic mixture of methylfolate to work in their brain. Some of us lucky folks have a defect in the CYP450 enzyme that’s key for metabolizing a host of drugs so even if we take huge doses of methylfolate we (probably) won’t get enough l-methylfolate.

    There’s also a single allele anomaly in a gene involved in methionine metabolism that’s probably overhyped into the realm of quackery so there’ll be people snapping up l-methylfolate (in the same way gluten-free folks snap up gluten free food without need- edit out if you wish). That’s not the real issue here- CYP450 enzyme issues are a broader issue and when l-methylfolate helps us, we have a happy party. When insurance providers suggest folic acid as a substitute, I grumble and wait for the day when insurance reality catches up to my liver and brain, hoping I survive the blackness and despair long enough for that to happen.