Deprex is a natural herbal supplement designed to help you function optimally. It helps you deal with stress and anxiety by calming your mind and body. The problem is that it most contains homoeopathic ingredients, and many physicians are of the view that ingredients in homeopathy are so diluted that they become ineffective. The ingredients it contains do little or nothing to maintain a balance between norepinephrine and serotonin. Some of the ingredients are simply ineffective, while others seem to be under-dosed.
It contains St. Ignatius Bean or Ignatia Amara, which is supposed calm emotions of grief and hysteria. You cannot find great details about this ingredient and it certainly lacks enough scientific evidence to be considered an effective nootropic ingredient. Things are not very different for Avena Sativa (Oat straw), which is included in the blend to help you deal with insomnia and exhaustion. There are some claims regarding its testosterone-boosting abilities. However, there is insufficient evidence suggesting that it boosts testosterone or works as a sex booster. It may work a little when combined with other sex herbs, but it certainly does little to improve your brain health.
It is supposed to have sedative properties, which is another reason why some people think it may help with attention deficit disorder; however, there is no scientific evidence suggesting that Avena can offer these benefits. There are very few studies showing that Avena sativa or oat straw may work as a cognitive enhancer, but even those studies have used very high doses of this herb.
A clinical trial involving adults ages 40 to 65 showed that oat straw offers acute cognitive benefits. Participants were given either 800 mg or 1600 mg of oat straw and their cognitive performance was measured pre-dose and at 1, 2.5, 4, and 6 hours post-dose. The group that took the 800 mg dose experienced the most benefit in a variety of cognitively demanding tasks.
We are not sure if there is enough of this ingredient in Deprex, which is why it would not be wrong to suggest that Deprex is going to prove ineffective in most cases. Even the presence of DL-Phenylalanine does not change anything. L-phenylalanine is a building block of different proteins in the body. Your body converts it into L-tyrosine and then other neurotransmitters to help improve your mood and alleviate depression symptoms. Some preliminary research shows that L-phenylalanine can improve mood in depressed people.
DLPA (or the D- or L- form alone) reduced depression in 31 of 40 people in a preliminary trial. Some doctors suggest a one-month trial with 3–4 grams per day of phenylalanine for people with depression, although some researchers have found that even very low amounts—75–200 mg per day—were helpful in preliminary trials. In one double-blind trial, depressed people given 150–200 mg of DLPA per day experienced results comparable to that produced by an antidepressant drug.
While preliminary research looks promising, further research is needed to draw a firm conclusion regarding the effects of DL-Phenylalanine. Moreover, we have no idea if you are going to get enough of this ingredient in each serving of Deprex.
How to Take Deprex
Adults and children over 12 years of age: Take 2-4 capsules twice daily, or as directed by a physician.
Another ingredient found in this herbal supplement is L-tyrosine. It is supposed to work by increasing the levels of neurotransmitters in the brain. There is some evidence suggesting that tyrosine may help improve mood and cognitive function.
2 g of tyrosine in a protein-rich drink (taken five times daily to total 10 g) was able to reduce blood pressure and preserve cognition (as measured by a matching assignment, where there was less of a decrease at post-test relative to pretest) during a week of combat training in cadets, relative to carbohydrate isocaloric placebo. There was no significant influence on mood state.
As mentioned already, your body can use phenylalanine to make L-tyrosine, so there is really no need to include it in the blend when there is already phenylalanine in it. Moreover, it is important to note that most studies showing positive results have used very high doses of tyrosine; so again, you may not get enough from Deprex and experience no cognitive boost.
There is also St. John’s Wort in Deprex. Unfortunately, there is conflicting evidence regarding the efficacy of this ingredient. In fact, studies show that it does not work any better than a placebo for depression and stress. There is insufficient evidence to confirm that St. John’s wort can help treat PMS, anxiety disorder, insomnia, or OCDs. Some studies have noticed some benefits, but even they have used up to 900 mg a day.
The addition of Scutellaria laterifolia (skullcap) fails to add any value to Deprex. Some chemicals found in skullcap are supposed to reduce inflammation and cause sedation. It is therefore thought to have positive effects in people suffering from depression, but there is no scientific evidence to confirm if supplementing with skullcap can help treat stroke, anxiety, nervous tension, spasms, allergies, and even high cholesterol. Similarly, verbena officinalis may work as an antioxidant in the body and improve overall health a little, but it does nothing to directly affect your brain health. There is no scientific evidence confirming the use of verbena for any condition in humans.
- May not last over a couple of weeks
- May not work for everyone
- May cause several side effects and allergic reactions
- May come with under-dosed ingredients
- May cost you a lot more than other comparable products
Some ingredients in Deprex are not really required to boost cognition and reduce stress. Aspartic acid is one example. Your body can easily produce this nonessential amino acid and you are usually not deficient in it. The same holds true for L-glutamic acid. It also includes L-glutamine, but we really believe that there is no need to include it in the blend in place of other somewhat effective brain boosters, such as acetyl-L-carnitine, Ashwagandha, etc. You cannot find studies suggesting that L-glutamine can improve focus, memory or concentration. The problem with L-glutamine is that when you do not see results, you tend to take more of it. Higher doses can actually kill brain cells and complicate the whole thing. GABA also falls in the same category of ineffective ingredients. It is usually selected for its possible anxiolytic effect – it is supposed to improve sleep quality and enhance cognition. It lacks scientific evidence though; in fact, some studies have found that supplementing with GABA is a waste of time because it cannot cross the blood-brain barrier. Studies that have noticed some benefits have taken up to 1000 mg of GABA a day, which again does not seem to be the case with Deprex.
There are many homoeopathic ingredients in this herbal formulation, but they are quite ineffective too. Igntia amara, for instance, is supposed to help you with anxiety, but not many studies confirm its benefit. Animal studies have shown some promise, but there is no real evidence suggesting that Ignatia amara or other similar homoeopathic ingredients like Cimicifuga racemosa, lithium bromatum, or kali bromatum can help reduce anxiety and depression.
In terms of price, Deprex may not be a great option either. Why would you want to spend more than thirty bucks on a supplement that fails to produce any positive results? The recommended dose is 2-4 capsules taken twice a day, and considering the lower doses of many ingredients, you may have to take 4 capsules twice a day, meaning that a bottle of 60 capsules may last you a week or so. This is certainly not a great option. You can easily find much better nootropic supplements at a rather affordable price. So, avoid Deprex in the first place and try something better!
What Does Deprex Claim To Do?
Deprex helps people deal with stress, anxiety, and depression in a more efficient way. You will end up experiencing several health-related problems due to chronic stress, and Deprex claims to help you in this regard by providing you with natural herbs and homoeopathic ingredients that produce quick results. Here are some of its claimed benefits:
- It helps change mood by raising serotonin levels.
- It helps maintain a balance between norepinephrine and serotonin.
- It helps you get rid of feelings of melancholy.
- It helps improve memory and boost cognitive function.
- It works to calm and diminish hypersensitivity.
Does Deprex Work?
Deprex claims to help you deal with mental and physical stress in an efficient way. It includes a long list of homoeopathic and herbal ingredients, but unfortunately, it fails to produce desired results. Most homoeopathic ingredients are often diluted to an extent that they become quite ineffective. Many other ingredients seem under-dosed, such as Avena sativa, phenylalanine, and more. Some ingredients do not deserve to be in a high quality nootropic supplement – GABA, L-tyrosine, glutamic acid, and L-glutamine are some examples. What it means is that you may notice some improvement in focus, but nothing more than that. Therefore, it is better to avoid Deprex in the first place and try something with scientifically proven ingredients and positive customer reviews.
What Are The Ingredients of Deprex?
Deprex contains a number of ingredients, but most of its active ingredients lack enough scientific support. Here is what you are going to find in Deprex:
- Avena Sativa: It is supposed to work by stimulating your nervous system and relieving nervous exhaustion in return. It also claims to reduce neurological tremors, but there is not enough studies to confirm these benefits.
- Kali Phosphoricum: It is supposed to help relieve nerve-related agitations. It may also help alleviate tension headaches.
- Cimicifuga Racemosa: It is said to help people with heavy limbs – it reduces muscular pain and prevents cramps at the same time.
- GABA: It helps improve cognition and memory, but it may not prove that effective in a supplement form because of its low bioavailability.
- DL-Phenylalanine: Your body converts it to L-tyrosine to help regulate the levels of dopamine, serotonin, and norepinephrine to improve mood. It may or may not work, but it is certainly associated with some side effects.
Does Deprex Have Any Side Effects?
Deprex claims to have natural ingredients, but even then it can cause several side effects. It includes certain ingredients that can interact with other drugs. For instance, you should not take Deprex when you are taking MAO inhibitors because St. John’s Wort may interact with it.
Similarly, verbena may affect the way your body processes certain herbs, drugs, or supplements. For instance:
Verbena may interfere with the way the body processes certain drugs, herbs or supplements using the liver’s cytochrome P450 enzyme system. As a result, the levels of these drugs may be changed in the blood and may cause increased or decreased effects or potentially serious adverse reactions. Patients using any medications should check the package insert and speak with a qualified healthcare professional, including a pharmacist, about possible interactions.
Deprex contains D-form of phenylalanine, which is supposed to improve mood, but it can affect enzymatic activity in the body can lead to several side effects.
It is especially dangerous for pregnant women because it can lead to birth defects, including heart, nervous system, and facial abnormalities. Breastfeeding women should also avoid phenylalanine and Deprex.
Are There Any Customer Reviews For Deprex?
Deprex makes big claims, but unfortunately, you cannot find many positive customer reviews for Deprex. Most people are concerned about its high price tag.
I have been taking it for a while but have not seen any change in cognition or brain function.
It did not last a couple of weeks when I increased the dose after noticing no benefits. I do not think it deserves that much of attention. It is expensive and it is ineffective too.
Does Deprex Offer a Money-Back Guarantee?
Yes, it comes with a money-back guarantee, but some customer reviews suggest that getting a refund is never easy.
Where Can I Buy Deprex?
You can buy it from the official website or many other third-party retailers.