LifeVantage AXIO

LifeVantage AXIO claims to not only provide you with a clean energy that allows you to concentrate longer and better, but also guard against oxidative stress on the brain because of aging and environmental stressors. LifeVantage AXIO contains a blend of ingredients which may provide a fast hit of physical and mental energy when you need it, but also improve working memory, improve metabolism, mental endurance, and enhance your mood.

So, can LifeVantage AXIO help with concentration and protect your brain?

We investigate the claims that LifeVantage can unlock a pure energy that will help you focus more clearly and for longer, and explore whether the ingredients can provide protection against normal age-related deterioration of the brain.

LifeVantage AXIO Pros

  • Caffeine may help provide an energy boost
  • Some of the ingredients show promise in protecting against cognitive decline, but much more testing is required before it can be considered reliable

LifeVantage AXIO Cons

  • The proprietary blend means we do not know how much of each ingredient is in AXIO
  • The multi-level marketing scheme means that once assigned to a distributor you may find it hard to get away
  • There isn’t a 100% money-back guarantee, and it can only be returned unused
Watchdog Rejected

LifeVantage AXIO

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What You Need To Know About LifeVantage AXIO

LifeVantage Axio is an energy replacement supplement that aims to boost your physical energy and mental performance, without the jittery, hyperactive feeling you sometimes get drinking too much coffee or other energy drinks.

The product comes in a powder form contained in handy portion-ready sachets, which must be mixed with 12-16 ounces of cold water and mixed thoroughly.

LifeVantage claims to be a science-led outfit concentrating on nutrigenomics, which is the prolonging of life through nutriceuticals. As well as caffeine and vitamins, they say AXIO contains nrf2 ingredients, which are anti-oxidant ingredients to help guard against mental and physical deterioration.

What Are The Side Effects Of LifeVantage AXIO?

DMAE has been known to cause very serious birth defects in unborn infants, so anyone trying to conceive or already pregnant should avoid this product.

The main side effects can come from just a couple of the ingredients, but blood sugar spikes could be very serious to diabetics and this product should not be taken without first contacting a physician. It could also cause weight gain, bloating, and flatulence with prolonged use. Users may also notice skin irritations and rashes.

How Much Does LifeVantage AXIO Cost?

AXIO is an expensive product retailing at $60.99 for a pack of 30 sachets, or £50.99 a month with a subscription. If you sign up to monthly packs, you may find it hard to cancel, as you must give at least one month’s notice and this can only be done by calling customer services or logging into your ‘virtual office’.

It operates on a Multi-Level Marketing scheme, meaning they try to get you hooked up to one of their distributors who will no doubt do the hard sell to get you to subscribe to more products, as they earn a commission on each sale.

Our Verdict On LifeVantage AXIO

Whilst some of the ingredients are used in pharmaceutical settings and certainly seem to show some promise in protecting brain health, there are simply not enough studies in human trials to make them reliable.

The anti-oxidants may have some positive benefit cumulatively over time but as the ingredients are in a proprietary blend it is impossible to say if they are contained in a high enough dose to make them effective.

The vitamins it contains are no different to general multi-vitamins available on the market, and although they are in support of brain health and may help with stimulation, they are generally not deficient in a healthy population.

As one of the key marketing messages is about energy without the sugar and hidden calories, users should be aware that Maltodextrin is a carbohydrate known to spike blood sugar and can cause weight gain.

Overall, we do not recommend LifeVantage AXIO to our readers.

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LifeVantage AXIO Review

LifeVantage Axio is an energy supplement designed to improve concentration, working memory, mental endurance, and support brain health over time. It contains a range of ingredients, including some pharmaceuticals such as DMAE, that are thought to support cognitive function.

LifeVantage AXIO Facts

  • LifeVantage say they specialize in nutrigenomics or prolonging of life, by using supplements to increase health and minimize deterioration through aging
  • They are not regulated by the FDA, so their claims have not been investigated
  • AXIO is a stimulating product with the foremost purpose of giving you a quick energy hit

It contains caffeine to the equivalent of about one cup of coffee but there are other stimulants such as green tea and quercetin, which can be neuroactive. There is significant variance in how users to react to the stimulating ingredients, so it is difficult to say if this product will work for you.

How to Take LifeVantage AXIO

  • Add AXIO to 12-16 oz of water mid-morning, mid-afternoon and whenever you need a reliable boost in energy without the dreaded sugar crash. For a lighter flavor, mix with more water.

Many of the active ingredients are in a proprietary blend, so it is impossible to ascertain actual quantities of them.

LifeVantage AXIO Concerns:

  • DMAE is known to cause birth defects in unborn infants and is not suitable for those trying to conceive or pregnant

What Does LifeVantage AXIO Claim To Do?

LifeVantage AXIO claims to give you a hit of energy which will increase focus, improve memory, and give you more mental endurance, whilst protecting your brain over the long term with its anti-oxidant effects.

Does LifeVantage AXIO Work?

There is not enough medical evidence to support their claims at the moment, although DMAE holds some promise in protecting an older population. It is possible that users will experience a boost in energy, but this is mainly owing to the caffeine and may be similar to drinking coffee or an energy drink.

What Are The Ingredients of LifeVantage AXIO?

  • Niacin 24mg (As Nicotinic Acid): Otherwise known as vitamin B3, is often thought to have protective effects on the cardiovascular system and secondarily on cognition and longevity. However, there is not much scientific evidence to support this currently, and there are also concerns that prolonged use may increase insulin resistance as it may prohibit the ability for the body to process blood glucose levels. Supplementation of Niacin can also create flushed skin, and there can be serious problems if overdosed. Source
  • Vitamin B6 (as Pyridoxine HCl) 2mg: Thought to have a few small benefits, particularly on energy and stimulation, but very few people are actually deficient in this vitamin and so there is no compelling reason to supplement it.
  • Vitamin B12 (as Methylcobalamin) 6mcg: Thought to help with the long-term support of cognitive function and has stimulating properties, but only the elderly and vegans are thought to need supplementation of this vitamin.
  • Magnesium (as Magnesium Aspartate) 10mg
  • Caffeine 100mg

Proprietary Blend 500mg:

  • DMAE Bitartrate: A compound used pharmaceutically to impact mental health by reducing age-related pigments, which can impair brain function and memory. It has the ability to act as an anti-oxidant and protect against stressors, which attack the healthy neurons of the brain. It also is known to have stimulatory effects. When supplemented at 1500mg per day in those with the onset of Alzheimer’s, it only had some small benefit over placebo studies, so the jury is very much out on whether this is a wonder drug. It is not suitable for those trying to conceive or pregnant women as it is known to be damaging to unborn infants, and people with a history of epilepsy should also avoid.
  • Green tea extract (Camellia sinensis) (Aerial): Comes from the leaves of the camellia sinensis plant, which are then steeped in water and consumed for its general health properties and for its stimulatory effects. It usually needs to be consumed in large quantities to have any profound effect.
  • Quercetin Dihydrate: A bioflavonoid typically found in high concentrations in apples and onions. It has anti-oxidant properties but is difficult to absorb into the system, meaning it may not be that effective when taken alone. Combined with other ingredients, particularly green tea, it can have a neuroactive effect, but results are varied and there is a wide degree of variability in efficacy with users. Doses of between 1200 – 2200mg daily may be expected when used in isolation.
  • Monterey Pine Extract (Pinus radiata) (Bark): Thought to increase blood flow and as a result is used for cardiovascular health, diabetic treatment, and erectile dysfunction. There are few medical trials but those that are active are generally industry-funded, which may imply some bias. It is thought to have anti-oxidant and anti-inflammatory effects, with the latter showing most benefit when built up in the system over time. Doses of around 40-60mg twice daily are thought to have some benefit over time.
  • L-Theanine: An amino acid that is not available through food but when consumed is thought to have a slight relaxing and mood enhancing effect. When combined with caffeine, it has been known to improve attention and inhibit stress. It shares similar properties to compounds found in green tea.
  • Other Ingredients: Maltodextrin, Natural Flavor, Citric Acid, Stevia (Leaf) Extract, Natural Color, Gum Acacia, Guar Gum, and Xanthan Gum.
  • (Maltodextrin): A food additive derived from starch, and it is largely present to help with water solubility and as a stabilizer for the other ingredients. It has received bad press lately for the side effects it can induce and the blood sugar spikes people have experienced. Whilst the amount is not known here, in high enough quantities people have reported weight gain, bloating, skin rashes, and difficulty breathing. Source

Does LifeVantage AXIO Have Any Side Effects?

Although LifeVantage does not list any potential side effects, some of the ingredients could cause the following issues:

  • Flushed skin
  • Weight gain
  • Bloating
  • Flatulence
  • Difficulty breathing
  • Asthma
  • Skin rashes
  • Insomnia
  • Headaches
  • Elevated blood pressure


Not recommended for children or individuals under 18 years of age, pregnant or nursing women or individuals sensitive to caffeine.

Are There Any Customer Reviews For LifeVantage AXIO?

The places you can buy AXIO are locked down pretty tight, so it is difficult to find recent customer reviews online. The only real scientific evidence to support claims comes from the caffeine in AXIO, where users may be likely to experience some energy increase.

Does LifeVantage AXIO Offer a Money-Back Guarantee?

This product can be purchased as a one-off but not before they try to hook you up to a local distributor, who will no doubt put the hard sell on you to subscribe. The cost is lower if you do sign up for a monthly auto-ship deal, which you can only get out of with one month’s notice and by contacting them through their ‘virtual office’. If you forget to cancel, you will continue to be sent and billed for products you may not want.

Refunds will only be given on unopened, unused product unless the product is defective, which is not a 100% guaranteed satisfaction policy.

Where Can I Buy LifeVantage AXIO?

AXIO is only available from the company website or through their approved distributors, of which there is thought to be over 65,000 worldwide. They operate on a multi-level marketing scheme, so they earn commission, bonuses, and benefits from selling to you.

They operate a strict policy that prohibits selling on third-party websites such as Amazon.

How does LifeVantage AXIO compare to OmniMind?

Criteria LifeVantage AXIO Comparison OmniMind
Clinically Proven Ingredients
Side Effect Free
Positive Customer Reviews
24/7 Support
Money-back Guarantee
LifeVantage AXIO

1.4 out of 5
LifeVantage AXIO Rating

The Nootropic Watchdog does not recommend LifeVantage AXIO.

  • Effectiveness
  • Safety
  • Price / Guarantee
The most popular consumer choice in 2021 is OmniMind

Containing ingredients that have been clinically tested and boasting a 30-day money-back guarantee, OmniMind is quickly rising to the top of the nootropic world.

Find out why people are choosing OmniMind to achieve advanced brain performance, and why it's our editor's top pick.

Read the Nootropic Watchdog OmniMind review here.

Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.

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