Herbal dietary supplements are taken for a variety of reasons, from improving athletic performance to losing weight. Despite their utility as handy pick-me-ups, it’s important to differentiate supplements from medicines. Unlike the medicines we receive from doctors, supplements are entirely unregulated, with the law allowing anyone (no matter how unqualified) to make a supplement out of herbal ingredients. As supplement manufacturers do not have to prove that their products work, the law protects us by not allowing them to be sold as medicines (for obvious reasons!) But not everyone follows the law…
Below we take an in-depth look into LifeVantage Protandim NRF1 Synergizer, to see whether this supposedly healing and anti-aging concoction has the cancer-curing properties its manufacturer once claimed.
LifeVantage Protandim NRF1 Synergizer Pros
- Has one effective ingredient that provides an antioxidant effect
- Few side effects
LifeVantage Protandim NRF1 Synergizer Cons
- Provides virtually no benefits, and does not have healing properties
- No money-back guarantee
- Ingredient quantities not listed
- Extremely expensive, and is essentially used to scam distributors
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LifeVantage Protandim NRF1 Synergizer Overview
What You Need To Know About LifeVantage Protandim NRF1 Synergizer
LifeVantage Protandim NRF1 Synergizer is a health supplement that contains a few herbal antioxidant ingredients. This product attracted significant criticism when it made a number of bold (and false) claims that it could prevent and cure cancer and diabetes. After making this shocking assertion on its advertising materials, the company received a warning letter from the FDA in 2017.
The manufacturer of Protandim NRF1 Synergizer, LifeVantage, is a multi-level marketing company. It functions by recruiting an army of independent distributors to sell the product on their behalf. The real victims of the scheme are the distributors themselves, almost all of whom will not be able to sell their (largely worthless and overpriced) stock.
What Are The Side Effects Of LifeVantage Protandim NRF1 Synergizer?
Some of the ingredients found in LifeVantage Protandim NRF1 Synergizer could cause side effects. Some of the potential side effects highlighted by the manufacturer and former customers include stomach and digestive issues, headaches, rashes, and lower blood pressure.
How Much Does LifeVantage Protandim NRF1 Synergizer Cost?
The official LifeVantage website sells a one-month supply of Protandim NRF1 Synergizer (containing 60 capsules) for $59.99. Customers signing up for a monthly subscription to the product can pay $49.99 per pack. Prices may be lower when purchasing from desperate LifeVantage distributors on eBay or in-person.
Our Verdict On LifeVantage Protandim NRF1 Synergizer
LifeVantage has thankfully stopped making ridiculous health claims about their products, which is encouraging. However, this doesn’t make Protandim NRF1 Synergizer any less useless.
Although it no longer claims that it cures cancer, the official website is still full of pseudoscientific nonsense about NRF1 and mitochondrial energy. However, all of this is just window dressing for what is a simple blend of cheap herbal ingredients. One of the active ingredients might actually provide an antioxidant effect, although customers could also harness this benefit by simply eating household ingredients like grapes. Customers should expect virtually no benefits from using this product.
In addition, Protandim NRF1 Synergizer is sinfully expensive for such a cheap mix, and like most junk products, it is not protected by a money-back guarantee. Although customers may get stung after purchasing this, the real victims of LifeVantage’s business model are their own distributors, many of whom are lumbered with stock that they won’t be able to sell or return for a full refund.
Overall, we recommend visiting the doctor for medical cures and avoiding the quackery of companies like LifeVantage.
We do not recommend LifeVantage Protandim NRF1 Synergizer to our readers.
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LifeVantage Protandim NRF1 Synergizer Key Features
LifeVantage Protandim NRF1 Synergizer is a health supplement that claims to have an anti-aging and cognitive-boosting effect. This simple blend of natural ingredients claims to nourish mitochondria, which can be thought of as the “power generators” of the body’s cells. Fuelling these is said to slow cellular aging and increase cellular energy, supposedly helping customers to feel more energetic, youthful, and healthy.
This product is produced and sold by LifeVantage, a multi-level marketing company based in Utah. LifeVantage is an extraordinarily controversial company. They have previously claimed that their Protandim products are able to cure cancer and diabetes, a shockingly-false claim that forced the FDA to issue a warning letter.
How to Take LifeVantage Protandim NRF1 Synergizer
The directions for use are as follows:
- Adults, take two capsules with food and a glass of water in the morning
The company has also been forced to issue a recall of Protandim in the past after allowing small metal fragments to contaminate their supply. In addition, the company has been subject to numerous large lawsuits, largely due to how they run things on the business side. Even as recently as 2018, the company was subject to another class action lawsuit accusing them of running a damaging pyramid scheme that harms their distributors.
LifeVantage Protandim NRF1 Synergizer Concerns:
- Built entirely on pseudoscience and likely does little to nothing
- Extraordinarily expensive for what is actually a very simple formula
- Important ingredient quantity information is missing
Customers looking to contact the company must, unfortunately, go through the helpline reserved for independent LifeVantage distributors (1(866) 460-7241) or via the distributor support email ([email protected]).
What Does LifeVantage Protandim NRF1 Synergizer Claim To Do?
The marketing backing LifeVantage Protandim NRF1 Synergizer makes a number of fairly modest claims that appear to be bigger than they are. Essentially, this product simply promises that customers will “feel healthier and more energetic”.
This improved feeling is supposedly the work of NRF1, a protein that regulates and increases the production of the mitochondria in our cells. Mitochondria are the energy source of our cells, so the manufacturers claim that this support effectively results in improved energy for our body all-round. They also claim that their formula promotes better overall cognitive and heart health, as well as promoting better cellular health by reducing “oxidative stress”.
Does LifeVantage Protandim NRF1 Synergizer Work?
The ingredients label fails to give us the important ingredient quantity information that we need. We know that the total volume of each 2-capsule dose is 790mg, which unfortunately tell us that almost every ingredient included in this product is too under-dosed to be effective (with the exception of alpha lipoic acid).
This product is essentially a collection of antioxidants, the vast majority of which are provided in too low a quantity (rendering them useless). The curious exception to this is alpha lipoic acid, which is hopefully dosed correctly; if it is, it could provide a useful antioxidant effect which is known to stave off the various diseases and conditions that afflict the elderly. There is nothing in this product that could provide an increase in energy.
What Are The Ingredients of LifeVantage Protandim NRF1 Synergizer?
The ingredients found in LifeVantage Protandim NRF1 Synergizer are listed below. Unfortunately, the manufacturer fails to provide any ingredient quantities, which can make it difficult or nearly impossible for customers/reviewers to estimate how effective the overall mix is. The quantity that is listed is correct for 2 capsules.
Proprietary Blend 790mg
- Acetyl-L-Carnitine: There is some evidence that supplementation of acetyl-l-carnitine can reduce body fat, although the strongest results were seen in the elderly. The ingredient also boosts energy levels, and is used to treat fatigue. It may also boost cognition in the elderly. The quantity used in this product is not clear but is likely too low to be effective. Source
- Quercetin: Known for AMPK activation, quercetin has antioxidant and anti-carcinogenic properties. It tends not to produce dramatic or consistent effects when tested on humans when compared to in-vitro tests. The quantity used in this supplement is far too low to be effective. Source
- Grape (Vitis vinifera) Skin, Pulp Extract: Grapes have been associated with numerous antibacterial and cancer prevention effects. However, just as you would not expect to receive such benefits after taking the tiniest nibble of a single grape, customers should also not expect any of these benefits to be present in the tiny quantity of grape contained in a capsule. Source
- Alpha Lipoic Acid: This ingredient is a potent antioxidant compound that works with the mitochondria in the cells. Supplementation could help to protect against the various diseases of aging. It also appears to suppress the appetite by inhibiting AMPK in the hypothalamus although little research has been conducted in humans at this point. Source
- CoEnzyme Q10: This coenzyme is found naturally in some foods and can be synthesized in the liver. Cells in the body harness it to produce energy and contribute to cell growth and maintenance. Its antioxidant effect may also protect the body from harmful molecules. It is also thought to boost energy levels and speed up recovery from exercise. Source
Does LifeVantage Protandim NRF1 Synergizer Have Any Side Effects?
According to LifeVantage, this product can cause allergic responses, gastrointestinal issues, headaches, and a skin rash appearing on the hands and feet.
L-carnitine is generally thought to be safe for use, although it can occasionally cause stomach problems, vomiting, heartburn, diarrhoea, seizures, and a fishy odour from the urine, sweat, and breath.
The use of Co-Enzyme Q10 can also sometimes lead to some mild side effects, which may include loss of appetite, nausea, vomiting, and diarrhoea. It may also lower blood pressure in some people.
Not suitable for pregnant or breastfeeding women. Not suitable for anyone under the age of 18. If you are taking any medications or are unsure about the suitability of this supplement for you, consult your doctor before purchase.
Are There Any Customer Reviews For LifeVantage Protandim NRF1 Synergizer?
We were able to find a handful of customer reviews on an old Amazon page, and most customers appeared to be happy with their purchase (though almost all mentioned the high price). It’s worth mentioning that many LifeVantage independent distributors pin their hopes (and life savings) on selling products like these, and have been known to flood review sections with positive and defensive comments about LifeVantage products. With that in mind, take some of the gushing praise with a pinch of salt.
Yes since I was diagnosed with multiple sclerosis few months back protandim has given me hope for the future. Only draw back is that it’s a little pricey especially since I’m a single father of two. Really wish insurance would offer a little help but unfortunately they won’t.
This product is a lifesaver. I have been taking it for over six months and I can honestly say I feel better for it. I constantly had a cough that even my doctor could not get rid of. Once I started taking this I noticed a great improvement in my cough. I feel healthier than I did before.
It gives me the energy boost I so desperately need. Thanks guys.
it’s ok i guess. i can’t tell if it’s helping me or not-i’ve been taking it for years now. it’s costly. people say my skin looks really good and that i look young for my age. so at least that’s something. it’s working to that degree so i keep buying it hoping for the best.
Does LifeVantage Protandim NRF1 Synergizer Offer a Money-Back Guarantee?
On the official LifeVantage website and terms of service, it is stated that all products returned within 30 days will receive a full refund. However, this offer only applies to unopened packages, and the company seems to make it very difficult to find their contact details online (the correct email is [email protected] for anyone interested).
These terms also don’t apply to independent distributors who might be interested in returning unsold stock, who have to pay restocking fees and jump through several hoops. We do not consider any of these terms to fit within our definition of a money-back guarantee.
Where Can I Buy LifeVantage Protandim NRF1 Synergizer?
Customers can buy a pack of LifeVantage Protandim NRF1 Synergizer on the official LifeVantage website. There is also an army of independent distributors looking to offload their stocks, and many sell cheaper packs online on eBay and occasionally on Amazon.
LifeVantage Protandim NRF1 Synergizer Rating
Price / Guarantee
The Nootropic Watchdog does not recommend LifeVantage Protandim NRF1 Synergizer.
Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.