Neurogenex is one of many nootropic supplements currently available in the market, but it claims to be different because it works by protecting neurotransmitters and improving their function at the same time. The question is, does it really help improve memory and reduce mental fatigue? Here is our review to help you decide.
Neurogenex is designed to help people who want to improve memory and overall health. It boosts the levels of different hormones and neurotransmitters by providing you with a number of natural herbs and extracts. It is also supposed to protect your brain from damage caused by neural metabolites. By increasing blood flow to your brain, Neurogenex improves focus and concentration. The manufacturer also claims that the regular use of Neurogenex increases nerve growth factor, which in turn increases nerve restoration and memory. While there are some impressive ingredients in the blend, you do not know exactly how much is available per serving. Moreover, there is no scientific evidence that the use of Neurogenex is going to improve brain function.
Neurogenex may seem to be a more authentic nootropic supplement because of its ingredient profile, but the truth is that it does nothing more than other nootropic supplements do. It makes big claims though. It is supposed to improve memory, mood, and cognitive function. It also claims to reduce symptoms of Alzheimer’s disease.
Unfortunately, there is not enough scientific evidence to confirm that the ingredients in Neurogenex will lead to a significant improvement in your brain function. Ingredients like Huperzine A, L-tyrosine, acetyl-L-carnitine, and even DMAE have a lot of hype attached to them, but they lack scientific support. There is also an issue of these ingredients being under-dosed in Neurogenex. You should not take this risk, especially considering the fact that Neurogenex may cost you up to $59.99.
Neurogenex claims to help you in many different ways. It is nootropic supplement, but it is also supposed to reduce weight by lowering appetite. It claims to work by supporting the neurotransmitter acetylcholine, which controls mood and appetite. Unfortunately, the ingredient profile of Neurogenex is not that impressive, and there is nothing in it that would make a significant change in your brain health.
There is Galantamine in Neurogenex, which is supposed to increase your brainpower by improving the nicotinic receptor activity. It claims to have an impact on your memory, mood, and appetite as well. Unfortunately, there is no real scientific evidence to support all these claims. It is worth mentioning that some studies that have found positive effects have also noted some serious gastrointestinal side effects associated with the use of Galantamine. For instance:
- The efficacy of galantamine has been tested in two randomised controlled trials for the treatment of vascular dementia and for a mixed population of Alzheimer’s disease patients with evidence of cerebrovascular disease on scanning. The rationale behind its use is to correct the cholinergic deficit seen in vascular dementia. This review found evidence of benefit for galantamine compared with placebo in measures of cognition in both studies. Both studies indicated higher rates of nausea and vomiting in patients taking galantamine compared with placebo. Source
As Galantamine works by increasing nicotinic receptor activity, it is never a preferred way to increase memory or treat Alzheimer’s disease. Similarly, Huperzine A is not going to make a huge difference to your memory or mood. Some studies show that it helps reduce symptoms of Alzheimer’s disease by increasing the levels of acetylcholine in the brain, but it is hard to find enough scientific data to confirm those findings. Many studies with positive results have low methodological quality. For instance:
- In a study involving a total of AD 454 patients, it was found that HupA might have some beneficial effects on improvement cognitive function, global clinical status, and functional performance.
The study showed positive results, but later studies and reviews could not find enough evidence to support those results. In fact, a Cochrane Review rejected it.
- The methodological quality of most included trials was not high, and that only one study was of adequate quality and size. The authors conclude that further large randomized multi-centre trials are warranted.
Then, there is Vinpocetine in Neurogenex. It is supposed to work by increasing the flow of blood to your brain, which in turn reduces mental fatigue. The problem is that some studies that have noted positive benefits of taking Vinpocetine have used very large doses. Modern day supplements do not have that much of Vinpocetine included in the blend, and we cannot say for sure if Neurogenex has enough of it or not.
How to Take Neurogenex
Here is what the official site says about taking Neurogenex:
- Take 1oz of the Neurogenex per day. You can even add it to your drinks.
L-tyrosine is a good ingredient included in the blend. There are some studies backing it up and suggesting that it may help improve mood and reduce mental fatigue. For instance:
- Relative to placebo, 100mg/kg L-Tyrosine was associated with significant improvements in mood, cognitive function, and side effects associated with acute stressors (cold and altitude) in military personnel. Heart rate and blood pressure were unaffected. Source
The problem is that you can see these effects only when you take enough of it daily. You should be taking up to 2g of l-tyrosine a day to see any benefits, and we are not sure if you are going to get this much from Neurogenex.
- 2g of Tyrosine in a protein rich drink (taken five times daily to total 10g) was able to reduce blood pressure and preserve cognition (as measured by a matching assignment, where there was less of a decrease at posttest relative to pretest) during a week of combat training in cadets, relative to carbohydrate isocaloric placebo. There was no significant influence on mood state. Source
You can also find acetyl-L-carnitine and bacopa monnieri in Neurogenex. Many supplement manufacturers say that acetyl-L-carnitine is effective, because it works to reduce the aging effects on your brain. Studies show that acetyl-L-carnitine may be beneficial but only for elderly people who may already have brain health issues and chronic fatigue syndrome. If you are looking for a way to prevent memory related problems, acetyl-L-carnitine and Neurogenex will not be of great assistance. The same can be said about bacopa monnieri that may have anti-anxiety effect but only in elderly people.
- Ineffective ingredients
- Possible under-dosed ingredients
- No information about money-back guarantee
- Possible side effects
- Very expensive
The manufacturer says that Neurogenex can help improve memory and energy levels because it also contains DMAE. They also say that supplementing with DMAE is a good way to reduce symptoms of Alzheimer’s disease. Studies do not back these claims though.
The effects of DMAE are actually quite unreliable. Some studies have noticed slight benefits too. For instance:
Still, you really do not need to spend a good amount of money to take Neurogenex and hope that it will work. Most of its ingredients are not supported by scientific studies, and 2-oxo-pyrrolidone is yet another example. It is supposed to boot memory recall mainly because it contains piracetam, but again, you need to take up to 4,800mg of piracetam a day to see its effects, and that is not what you are going to get from Neurogenex. Even if you get this much of Piracetam, there is not guarantee that you will notice positive results. For instance:
- An improved trend was noted with Piracetam at 8g for a period of one year in persons with Alzheimer’s disease, but this did not reach statistical significance. Source
The fact of the matter is that Neurogenex costs you a lot and provides you with ingredients that lack scientific support. You do not have information about how much of each ingredient is included in the formula, which is another concern keeping people from using Neurogenex. You will better off trying something with a clear ingredient profile and positive customer reviews. Neurogenex is not going to cut it!
What Does Neurogenex Claim To Do?
Neurogenex claims to help you in many ways and that is mainly because its ingredient profile is quite extensive. Here are some of its claimed benefits:
- Improves memory recall and function
- Improves your mood and regulate appetite
- Increases focus and concentration
- Increases blood flow to the brain to improve mental fatigue
Does Neurogenex Work?
Neurogenex is designed to help people worried about cognitive decline. It is supposed to work by improving the functioning of neurotransmitters in the brain. It certainly has some good natural ingredients, but most of those ingredients do not have enough scientific evidence to support their use. This is true for ingredients like Galantamine, bacopa monnieri, Huperzine A, and DMAE. Other ingredients, like L-tyrosine, acetyl-L-carnitine, and Vinpocetine may work, but those positive effects show when you take enough of these ingredients. With no information about how much of each ingredient is there in the blend, you cannot say for sure if Neurogenex is going to work or not. Therefore, you will be better off trying a supplement that comes with an impressive ingredient profile and includes scientifically proven ingredients in the blend. Neurogenex is not something that you would want to buy!
What Are The Ingredients of Neurogenex?
Neurogenex is a combination of several natural ingredients. Here are some of the main ingredients available in this nootropic supplement:
- 2-XO-Pyrrolidone: It is supposed to improve memory by increasing neural flow in brain hemispheres. It may also help increase density of cholinergic receptors, but there is no scientific evidence to support these claims.
- Vinpocetine: It works by increasing the supply of blood to your brain, but an increased blood supply is not always going to reverse any damage done to your brain.
- Galantamine: This acetylcholinesterase inhibitor is supposed to protect acetylcholine to improve mood and memory. There may be some serious side effects associated with its use though.
- Huperzine A: Just like Galantamine, it is supposed to work by protecting acetylcholine in the brain. It may improve your focus a little, but do not expect much from it though.
- DMAE: It is supposed to increase attention span by increasing levels of choline in your brain, but there is insufficient scientific evidence to support this claim.
- Acetyl-L-Carnitine: It works by protecting brain cells from oxidative damage, but you may not get enough of it from Neurogenex.
- Acetyl-L-Tyrosine: It helps increase the levels of dopamine in your brain, which in turn improves mood and reduces symptoms of depression. It is not clear how much of it is available in Neurogenex.
Does Neurogenex Have Any Side Effects?
It is true that Neurogenex contains natural ingredients, but it does not automatically mean that it will not cause any side effects. In fact, some of its ingredients may not suit every one. For instance, Galantamine is supposed to improve memory and offer other benefits, but several studies have confirmed that it may lead to serious gastrointestinal side effects. These side effects may become serious considering the fact that you also have Huperzine A and bacopa monnieri in the blend.
There is also DMAE in Neurogenex, which works by increasing the levels of feel-good hormone, but many people have complained about several side effects after taking DMAE supplements. Some common issues include bloating, depression, pain in the neck, constipation, irritability, and confusion.
L-tyrosine in Neurogenex may also be responsible for causing serious changes in brain chemicals. Along with many other issues, this chemical imbalance may trigger migraine headaches. Some people have also complained about experiencing sleep problems after supplementing with L-tyrosine. Other ingredients in Neurogenex are also responsible for causing side effects such as vomiting, nausea, blurred vision, slurred speech, restlessness, and twitching of muscle fibers. Be sure to avoid it if you are taking any medications. You should also avoid Neurogenex if you are pregnant or breastfeeding.
Are There Any Customer Reviews For Neurogenex?
Neurogenex seems to be a promising nootropic supplement, but unfortunately, it fails to deliver positive results, and that is the reason why you cannot find enough positive customer reviews for it. Here are some examples.
This supplement has done nothing for me. I am not going to buy it again.
I do not think it does anything to improve your concentration or memory. It does leave you with headaches and GI problems.
Does Neurogenex Offer a Money-Back Guarantee?
There is no clear information about any money-back guarantee. It is better to avoid buying it in the first place.
Where Can I Buy Neurogenex?
You can buy it from third-party retailers, however it seems to be either sold out or discontinued.